{"id":327049,"date":"2025-03-03T12:45:53","date_gmt":"2025-03-03T18:45:53","guid":{"rendered":"https:\/\/www.liveaction.org\/news\/?p=327049"},"modified":"2025-03-03T08:36:21","modified_gmt":"2025-03-03T14:36:21","slug":"hope-preborn-baby-cured-disorder-prenatal-treatment","status":"publish","type":"post","link":"https:\/\/archive.liveaction.org\/news\/hope-preborn-baby-cured-disorder-prenatal-treatment\/","title":{"rendered":"&#8216;Real hope&#8217;: Preborn baby girl cured of rare genetic disorder through prenatal treatment"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><p><span style=\"font-weight: 400;\">For the first time, physicians have <\/span><a href=\"https:\/\/www.sciencealert.com\/fetus-receives-life-saving-medication-inside-womb-in-medical-first\"><span style=\"font-weight: 400;\">successfully cured<\/span><\/a><span style=\"font-weight: 400;\"> a child of a rare disorder known as type 1 spinal muscular atrophy (SMA) by beginning treatment while she was still in the womb.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a new study, physicians have documented how a preborn child was treated for SMA through her mother taking the medication while still pregnant, rather than waiting for the child to be born to administer treatment. The report details how the child absorbed the medication through her mother\u2019s umbilical cord and amniotic fluid.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Now, after two and a half years outside the womb, the child has shown no signs of having SMA, leading pediatric neurologist Michelle Farrar <\/span><a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00534-0\"><span style=\"font-weight: 400;\">to determine<\/span><\/a><span style=\"font-weight: 400;\"> that she has been \u201ceffectively treated, with no manifestations of the condition.\u201d<\/span><\/p>\n<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/S-lQOooYAs8?si=M8lWsMqPfAI7dhD-\" width=\"640\" height=\"355\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">\ufeff<\/span><\/iframe><\/p>\n<p><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/spinal-muscular-atrophy-life-expectancy#life-expectancy\"><span style=\"font-weight: 400;\">Type 1 SMA<\/span><\/a><span style=\"font-weight: 400;\"> is a form of neuromuscular disorder characterized in infants by lack of head control, decreased muscle tone, and difficulty breathing and swallowing. SMA typically manifests in children by the age of six months and ultimately results in death by age two.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Notably, the potential to heal SMA in the womb may save many lives from being discarded as embryos through the in vitro fertilization (IVF) process. Parents at risk of passing along the gene that causes SMA are <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/14505-spinal-muscular-atrophy-sma\"><span style=\"font-weight: 400;\">often encouraged<\/span><\/a><span style=\"font-weight: 400;\"> to pursue parenthood through IVF rather than natural means in order to pre-screen embryos for the disorder. Parents are then encouraged to implant \u201chealthy\u201d embryos and abandon those found to carry the SMA gene.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">SMA is not the first serious condition to be successfully treated through prenatal care. <\/span><span style=\"font-weight: 400;\">According to the <\/span><a href=\"https:\/\/lozierinstitute.org\/dive-deeper\/fetal-surgery-treating-babies-before-they-are-born\/\"><span style=\"font-weight: 400;\">Charlotte Lozier Institute<\/span><\/a><span style=\"font-weight: 400;\">, fetal surgery has also proven highly effective at treating conditions such as spina bifida, twin-to-twin transfusion syndrome, and severe kidney and bladder obstructions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cAmidst the pain and despair of receiving a fetal diagnosis, fetal therapy and surgical interventions provide real hope to parents,\u201d reads a section on fetal surgery from the resource. \u201cIt is now possible for fetuses with previously life-limiting or life-threatening diagnoses to not only survive to birth, but also to experience marked increases in quality of life and lifespan.\u201d<\/span><\/p>\n<p><a href=\"https:\/\/actnow.io\/Vety0KE\"><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-large wp-image-325597\" src=\"https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1-700x251.png\" alt=\"\" width=\"700\" height=\"251\" srcset=\"https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1-700x251.png 700w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1-300x107.png 300w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1-768x275.png 768w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1-500x179.png 500w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2025\/01\/LA25DefundPP_EmailBannerAd-02-1.png 1167w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the first time, physicians have successfully cured a child of a rare disorder known as type 1 spinal muscular atrophy (SMA) by beginning treatment while she was still in the womb.\u00a0 In a new study, physicians have documented how a preborn child was treated for SMA through her mother taking the medication while still [&hellip;]<\/p>\n","protected":false},"author":1023,"featured_media":225791,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false},"categories":[9455,3473],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>&#039;Real hope&#039;: Preborn baby girl cured of 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