{"id":306652,"date":"2024-02-10T09:31:52","date_gmt":"2024-02-10T15:31:52","guid":{"rendered":"https:\/\/www.liveaction.org\/news\/?p=306652"},"modified":"2024-08-08T13:57:07","modified_gmt":"2024-08-08T18:57:07","slug":"big-abortion-pill-reversal-decrease-effectiveness","status":"publish","type":"post","link":"https:\/\/archive.liveaction.org\/news\/big-abortion-pill-reversal-decrease-effectiveness\/","title":{"rendered":"PROOF: Big Abortion knows hormone used for &#8216;abortion pill reversal&#8217; can decrease abortion pill&#8217;s effectiveness"},"content":{"rendered":"<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div><p>UPDATE, 8\/8\/24: On August 6, the Centers for Disease Control and Prevention (CDC) updated their &#8220;<a href=\"https:\/\/www.cdc.gov\/contraception\/hcp\/usspr\/?CDC_AAref_Val=https:\/\/www.cdc.gov\/reproductivehealth\/contraception\/mmwr\/spr\/summary.html\">U.S. Selected Practice Recommendations for Contraceptive Use<\/a>.&#8221; The document provides additional evidence that mainstream medical authorities are aware that progesterone (which is used for so-called &#8220;Abortion Pill Reversal&#8221;) can interfere with the efficacy of mifepristone. It clearly states that &#8220;concurrent administration of DMPA [synthetic progesterone] with mifepristone might slightly decrease medication abortion effectiveness and increase risk for ongoing pregnancy.&#8221;<\/p>\n<div id=\"attachment_316849\" style=\"width: 910px\" class=\"wp-caption aligncenter\"><img aria-describedby=\"caption-attachment-316849\" decoding=\"async\" loading=\"lazy\" class=\"wp-image-316849\" src=\"https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-700x107.jpeg\" alt=\"\" width=\"900\" height=\"137\" srcset=\"https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-700x107.jpeg 700w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-300x46.jpeg 300w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-768x117.jpeg 768w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-1536x234.jpeg 1536w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-2048x313.jpeg 2048w, https:\/\/archive.liveaction.org\/news\/wp-content\/uploads\/2024\/02\/EF8CCCBA-95D6-488C-8276-813A4D7513B2_1_201_a-500x76.jpeg 500w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><p id=\"caption-attachment-316849\" class=\"wp-caption-text\">Screenshot from updated CDC practice recommendations for contraceptive use<\/p><\/div>\n<p>2\/10\/24: <span style=\"font-weight: 400;\">On Tuesday, February 6, the <\/span><a href=\"https:\/\/www.thomasmoresociety.org\/\"><span style=\"font-weight: 400;\">Thomas More Society<\/span><\/a><span style=\"font-weight: 400;\"> published a <\/span><a href=\"https:\/\/www.thomasmoresociety.org\/news\/heartbeat-international-fights-back-against-californias-attempt-to-force-women-to-abort-their-babies\"><span style=\"font-weight: 400;\">press release<\/span><\/a><span style=\"font-weight: 400;\"> detailing their <\/span><a href=\"https:\/\/www.thomasmoresociety.org\/case\/the-people-of-the-state-of-california-v-heartbeat-international-realoptions\"><span style=\"font-weight: 400;\">petition<\/span><\/a><span style=\"font-weight: 400;\"> to the California Supreme Court for dismissal of a <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/glaring-issues-california-ag-abortion-pill-reversal\/\"><span style=\"font-weight: 400;\">lawsuit<\/span><\/a><span style=\"font-weight: 400;\"> filed by California Attorney General <a href=\"https:\/\/oag.ca.gov\/about\">Rob Bonta<\/a> against their clients \u2014 <\/span><a href=\"https:\/\/www.heartbeatinternational.org\/\"><span style=\"font-weight: 400;\">Heartbeat International<\/span><\/a><span style=\"font-weight: 400;\"> (HBI) and <\/span><a href=\"https:\/\/www.realoptions.net\/\"><span style=\"font-weight: 400;\">RealOptions Obria Medical Clinics<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/california-lawsuit-pregnancy-resource-centers\/\"><span style=\"font-weight: 400;\">lawsuit<\/span><\/a><span style=\"font-weight: 400;\"> alleges that the two pro-life organizations are \u201cmisleading patients\u201d by offering them information about the administration of progesterone to attempt to counter the effects of the abortion pill mifepristone. This treatment is most commonly referred to as &#8220;<\/span><a href=\"https:\/\/archive.liveaction.org\/news\/4000-lives-saved-abortion-pill-reversal\/\"><span style=\"font-weight: 400;\">abortion pill reversal<\/span><\/a>&#8220;<span style=\"font-weight: 400;\"> (APR). The suit <\/span><a href=\"https:\/\/www.thomasmoresociety.org\/case\/the-people-of-the-state-of-california-v-heartbeat-international-realoptions\"><span style=\"font-weight: 400;\">accuses<\/span><\/a><span style=\"font-weight: 400;\"> HBI and RealOptions of making \u201cfalse or misleading statements\u201d and engaging in \u201cunlawful, unfair, and fraudulent business practices.\u201d<\/span><\/p>\n<p><b>THE TRUTH ABOUT APR<\/b><\/p>\n<p><span style=\"font-weight: 400;\">To support these allegations, Bonta\u2019s <\/span><a href=\"https:\/\/oag.ca.gov\/system\/files\/attachments\/press-docs\/FINAL%20-%20Complaint%20-%20Ppl%20v%20Heartbeat%20Intl%2C%20et%20al%20%28APR%29.pdf\"><span style=\"font-weight: 400;\">lawsuit<\/span><\/a> <a href=\"https:\/\/oag.ca.gov\/news\/press-releases\/attorney-general-bonta-sues-anti-abortion-group-five-california-crisis-pregnancy\"><span style=\"font-weight: 400;\">claims<\/span><\/a><span style=\"font-weight: 400;\"> that APR is \u201can unproven and largely experimental procedure\u201d which is \u201cnot backed by credible science.\u201d In their petition filed on Tuesday, Thomas More Society attorneys cite ample evidence to the contrary.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Live Action News has repeatedly reported on APR\u2019s <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/abortion-pill-reversal-safe-doctor-explains\/\"><span style=\"font-weight: 400;\">mechanism of action<\/span><\/a><span style=\"font-weight: 400;\"> \u2013 it essentially works by supplementing the mother with the hormone progesterone to counteract the effects of mifepristone (the first drug in the abortion pill regimen), which inhibits the pregnancy-sustaining action of the woman\u2019s naturally occurring progesterone. Live Action News has also reported on APR\u2019s stated <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/report-abortion-pill-reversal-safety-efficacy\/\"><span style=\"font-weight: 400;\">safety and efficacy<\/span><\/a><span style=\"font-weight: 400;\"> and has published <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/abortion-pill-reversal-saves\/\"><span style=\"font-weight: 400;\">numerous<\/span><\/a> <a href=\"https:\/\/archive.liveaction.org\/news\/sarah-abortion-pill-reversal-saved-baby\/\"><span style=\"font-weight: 400;\">stories<\/span><\/a><span style=\"font-weight: 400;\"> of <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/mom-grateful-daughter-abortion-pill-reversal\/\"><span style=\"font-weight: 400;\">women<\/span><\/a><span style=\"font-weight: 400;\"> who were said to have been able to <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/amrita-abortion-pill-reversal-daughter\/\"><span style=\"font-weight: 400;\">save<\/span><\/a><span style=\"font-weight: 400;\"> their <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/abortion-pill-reversal-pregnancy-saved-life\/\"><span style=\"font-weight: 400;\">children\u2019s<\/span><\/a> <a href=\"https:\/\/archive.liveaction.org\/news\/baby-not-alive-mom-abortion-pill-reversal\/\"><span style=\"font-weight: 400;\">lives<\/span><\/a><span style=\"font-weight: 400;\"> by <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/abortion-pill-reversal-son-may-never-born\/\"><span style=\"font-weight: 400;\">following<\/span><\/a><span style=\"font-weight: 400;\"> the <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/mom-son-second-chance-abortion-pill-reversal\/\"><span style=\"font-weight: 400;\">APR<\/span><\/a> <a href=\"https:\/\/archive.liveaction.org\/news\/abortion-pill-reversal-hotline-saved-son\/\"><span style=\"font-weight: 400;\">protocol<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><b>WHAT DO PRO-ABORTION SOURCES SAY?<\/b><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s interesting to note, however, that even the <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/exposing-acog-medical-organization-supports-abortion-industry\/\"><span style=\"font-weight: 400;\">pro-abortion<\/span><\/a><span style=\"font-weight: 400;\"> American College of Obstetricians and Gynecologists (ACOG) has previously <\/span><a href=\"https:\/\/archive.liveaction.org\/news\/acog-bulletin-doctors-progesterone-interfere-abortion-pill\/\"><span style=\"font-weight: 400;\">noted<\/span><\/a><span style=\"font-weight: 400;\"> that progesterone <em>can inhibit the efficacy of mifepristone<\/em>.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In ACOG\u2019s 2020 medication abortion <\/span><a href=\"https:\/\/www.acog.org\/clinical\/clinical-guidance\/practice-bulletin\/articles\/2020\/10\/medication-abortion-up-to-70-days-of-gestation\"><span style=\"font-weight: 400;\">practice bulletin<\/span><\/a><span style=\"font-weight: 400;\">, which provides information to doctors who prescribe the abortion pill, it states: \u201c[A]dministration of DMPA on day 1 of the medication abortion regimen may increase the risk of ongoing pregnancy.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">DMPA is a method of long-acting birth control frequently referred to by its brand name, <\/span><a href=\"https:\/\/www.plannedparenthood.org\/learn\/birth-control\/birth-control-shot\"><span style=\"font-weight: 400;\">Depo-Provera<\/span><\/a><span style=\"font-weight: 400;\">. It <\/span><a href=\"https:\/\/www.pfizermedicalinformation.com\/depo-provera\"><span style=\"font-weight: 400;\">relies<\/span><\/a><span style=\"font-weight: 400;\"> upon <strong>synthetic progesterone<\/strong> for its contraceptive efficacy. In layman&#8217;s terms, ACOG\u2019s above statement essentially warns doctors that administering progesterone \u2013 even in its synthetic form \u2013 immediately after mifepristone <strong>can prevent the abortion pill from being \u201csuccessful.\u201d\u00a0<\/strong><\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">This is precisely what APR advocates assert,<\/span><\/i><span style=\"font-weight: 400;\"> and this is the exact same mechanism of action relied upon by the APR protocol.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The ACOG practice bulletin references a 2016 <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27607859\/\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\">, which found that \u201c[o]ngoing pregnancy after initial abortion treatment was significantly more common\u201d in women who had been given DMPA <\/span><i><span style=\"font-weight: 400;\">with<\/span><\/i><span style=\"font-weight: 400;\"> mifepristone compared to those who had been given DMPA <\/span><i><span style=\"font-weight: 400;\">after<\/span><\/i><span style=\"font-weight: 400;\"> their abortions were complete.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A more recent (November 2023) <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S001078242300286X\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> in the journal Contraception reached the same conclusion: \u201cConcurrent administration of DMPA with mifepristone may decrease medication abortion efficacy.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The World Health Organization (WHO) also <\/span><a href=\"https:\/\/srhr.org\/abortioncare\/chapter-3\/post-abortion-3-5\/post-abortion-contraception-recommendations-41-47-3-5-4\/\"><span style=\"font-weight: 400;\">states<\/span><\/a><span style=\"font-weight: 400;\"> on its \u201cabortion care guideline\u201d page: \u201cImmediate initiation of intramuscular depot medroxyprogesterone acetate (DMPA) is associated with a slight decrease in the effectiveness of medical abortion regimens.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Similarly, the <\/span><a href=\"https:\/\/www.reproductiveaccess.org\/about\/\"><span style=\"font-weight: 400;\">pro-abortion<\/span><\/a><span style=\"font-weight: 400;\"> Reproductive Health Access Front <\/span><a href=\"https:\/\/www.reproductiveaccess.org\/resource\/contraceptive-pearls-post-abortion-contraception\/\"><span style=\"font-weight: 400;\">claims<\/span><\/a><span style=\"font-weight: 400;\"> that \u201cthere is some evidence that Depo Provera decreases the effectiveness of mifepristone. Patients who choose Depo after a medication abortion \u2026 can receive the shot the same day if they accept possible decrease in effectiveness[.]\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Innovating Education in Reproductive Health, another <\/span><a href=\"https:\/\/www.innovating-education.org\/about-us-2\/\"><span style=\"font-weight: 400;\">pro-abortion<\/span><\/a><span style=\"font-weight: 400;\"> organization, likewise <\/span><a href=\"https:\/\/www.innovating-education.org\/2016\/07\/can-give-depo-nexplanon-day-medication-abortion\/#:~:text=Mifepristone%20binds%20to%20progesterone%20receptors,mifepristone%20and%20decrease%20its%20efficacy\"><span style=\"font-weight: 400;\">claims<\/span><\/a><span style=\"font-weight: 400;\">: \u201cMifepristone binds to progesterone receptors; its affinity for the receptor is higher than that of progesterone itself. <strong>Administering progesterone<\/strong> in the depot or implant form at the same time <strong>could potentially out-compete mifepristone and decrease its efficacy<\/strong>.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">O&amp;G Magazine, a publication of the Royal Australian and New Zealand College of Obstetricians and Gynaecologists, also <\/span><a href=\"https:\/\/www.ogmagazine.org.au\/20\/2-20\/post-abortion-contraception\/\"><span style=\"font-weight: 400;\">warns<\/span><\/a><span style=\"font-weight: 400;\">: \u201cIn the context of medical abortion, there is some concern that initiation of DMPA at the time of mifepristone administration may impair the progesterone-blocking action of mifepristone, reducing medical abortion efficacy.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In other words, numerous sources, none of whom have any affiliation with APR, and many of whom actively promote abortion, make the same claim that APR providers do, namely: <em>progesterone can decrease the effectiveness of the first drug in the abortion pill regimen after it has already been ingested<\/em>.<\/span><\/p>\n<p><b>AN INSIDIOUS DOUBLE-STANDARD<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Some of the above sources not only affirm this claim, but emphasize that women should be informed about it. The 2023 <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S001078242300286X\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> published in Contraception states: \u201cPatients seeking medication abortion should be informed about these findings to help guide post-abortion contraceptive choices.\u201d <\/span><\/p>\n<p><span style=\"font-weight: 400;\">And O&amp;G Magazine <\/span><a href=\"https:\/\/www.ogmagazine.org.au\/20\/2-20\/post-abortion-contraception\/\"><span style=\"font-weight: 400;\">agrees<\/span><\/a><span style=\"font-weight: 400;\">: \u201cWomen having a medical abortion should \u2026 be advised that there may be a slightly higher risk of continuing pregnancy if DMPA is initiated at the time of mifepristone administration.\u201d Even ACOG <a href=\"https:\/\/www.acog.org\/clinical\/clinical-guidance\/practice-bulletin\/articles\/2020\/10\/medication-abortion-up-to-70-days-of-gestation\">says<\/a> &#8220;[p]atients who select depot medroxyprogesterone acetate (DMPA) for contraception&#8221; after taking the abortion pill &#8220;should be counseled&#8221; about DMPA&#8217;s ability to impact the efficacy of mifepristone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But when <em>pro-life<\/em> organizations attempt to do exactly what is advised by these publications \u2013 namely, inform women that progesterone can stop a chemical abortion already in-progress \u2013 they face lawsuits and other forms of retaliation from abortion advocates.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There is an insidious double-standard at play here. The <\/span><i><span style=\"font-weight: 400;\">exact same information<\/span><\/i><span style=\"font-weight: 400;\"> is hailed as \u201cscience\u201d when pro-abortion sources report it, but is denounced as quackery when proclaimed by pro-lifers.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Clearly, in the eyes of abortion advocates like AG Rob Bonta, the real crime being committed by organizations like HBI and RealOptions is that of saving lives by utilizing this information \u2014 which is in no way &#8220;pseudoscience.&#8221; Accusations that they are disseminating \u201cmisinformation\u201d are merely a flimsy cover for what is solely and decidedly an ideology-driven attack.<\/span><\/p>\n<p><em>Editor&#8217;s Note 7\/30\/24: This post has been updated for clarification.<\/em><\/p>\n<p class=\"p1\" style=\"text-align: center;\"><span class=\"s1\"><a href=\"https:\/\/www.liveaction.org\/tell-congress-stop-the-doj-from-targeting-pro-life-americans\/?utm_campaign=doj_petition&amp;utm_medium=lan_website\"><b><i>The DOJ put a pro-life grandmother in jail for protesting the killing of preborn children. Please take 30-seconds to TELL CONGRESS: STOP THE DOJ FROM TARGETING PRO-LIFE AMERICANS.<\/i><\/b><\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>UPDATE, 8\/8\/24: On August 6, the Centers for Disease Control and Prevention (CDC) updated their &#8220;U.S. Selected Practice Recommendations for Contraceptive Use.&#8221; The document provides additional evidence that mainstream medical authorities are aware that progesterone (which is used for so-called &#8220;Abortion Pill Reversal&#8221;) can interfere with the efficacy of mifepristone. It clearly states that &#8220;concurrent [&hellip;]<\/p>\n","protected":false},"author":788,"featured_media":289195,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false},"categories":[10627,9459],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>PROOF: Big Abortion knows hormone used for &#039;abortion pill reversal&#039; can decrease abortion pill&#039;s effectiveness<\/title>\n<meta name=\"description\" content=\"The same information is hailed as \u201cscience\u201d when pro-abortion sources report it, but is denounced as quackery when proclaimed by pro-lifers.\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/archive.liveaction.org\/news\/big-abortion-pill-reversal-decrease-effectiveness\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PROOF: Big Abortion knows hormone used for &#039;abortion pill reversal&#039; 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